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SPP2

Description secreted phosphoprotein 2
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Endoplasmic Reticulum Lumen
  • Platelet Dense Granule Lumen
  • Protein-containing Complex
Molecular Function
  • Endopeptidase Inhibitor Activity
Biological Process
  • Skeletal System Development
  • Bone Remodeling
  • Protein-containing Complex Assembly
Pathways
  • Platelet degranulation
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Post-translational protein phosphorylation
Drugs
Diseases
GWAS
  • Cognitive decline (age-related) ( 28078323)
  • Hair greying ( 26926045)
  • Osteoporosis-related phenotypes ( 20548944)
  • Triglyceride levels ( 30108155)
Novel Interacting Genes 1 novel interacting genes: PIGS
Interacting Genes
Entrez ID 6694
HPRD ID 04029
Ensembl ID ENSG00000072080
Uniprot IDs Q13103
PDB IDs
Enriched GO Terms of Interacting Partners?
  • GPI-anchor Transamidase Complex
  • Attachment Of GPI Anchor To Protein
  • GPI Anchored Protein Biosynthesis
  • GPI Anchor Metabolic Process
  • GPI Anchor Biosynthetic Process
  • Glycolipid Biosynthetic Process
  • Glycolipid Metabolic Process
  • Phosphatidylinositol Biosynthetic Process
  • Phosphatidylinositol Metabolic Process
  • Membrane Lipid Metabolic Process
  • Glycerophospholipid Biosynthetic Process
  • Phospholipid Biosynthetic Process
  • Glycerophospholipid Metabolic Process
  • Phospholipid Metabolic Process
  • Protein Maturation
  • Glycerolipid Metabolic Process
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