SOAT1

Gene Name		sterol O-acyltransferase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Fatty-acyl-CoA Binding Sterol O-acyltransferase Activity Protein Binding Cholesterol Binding Cholesterol O-acyltransferase Activity
	Biological Process	Cholesterol Metabolic Process Macrophage Derived Foam Cell Differentiation Cholesterol Storage Cholesterol Efflux Very-low-density Lipoprotein Particle Assembly Cholesterol Esterification Cholesterol Homeostasis Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process
Pathways
Drugs		Ezetimibe Hesperetin
Diseases
GWAS
Protein-protein Interactions		1 interactors: TERF1
Entrez ID		6646
HPRD ID		00033
Ensembl ID		ENSG00000057252
Uniprot IDs		P35610
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Negative Regulation Of Telomere Maintenance Via Telomerase Replicative Cell Aging Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Nuclear Cell Cycle DNA Replication Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Microtubule Polymerization Regulation Of Telomerase Activity Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Microtubule Polymerization Telomere Maintenance Via Telomere Lengthening Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation Regulation Of DNA Biosynthetic Process Spindle Checkpoint Negative Regulation Of DNA Replication Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Cell Aging Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Cellular Protein Catabolic Process Telomere Maintenance Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Polymerization Regulation Of Mitotic Nuclear Division Regulation Of DNA Replication Positive Regulation Of Cell Division Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Microtubule Cytoskeleton Organization Mitotic Cell Cycle Checkpoint
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