SMARCD2

Description		SWI/SNF related BAF chromatin remodeling complex subunit D2
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Chromatin Nucleus Nucleoplasm Nuclear Matrix SWI/SNF Complex RSC-type Complex Protein-containing Complex Brahma Complex BBAF Complex
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding
	Biological Process	Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of T Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of G0 To G1 Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the polybromo-BAF (pBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301)
Interacting Genes		5 interacting genes: CEBPA NOTCH2NLA OGT UNKL XRN1
Entrez ID		6603
HPRD ID		03439
Ensembl ID		ENSG00000108604
Uniprot IDs		J3KMX2 Q92925
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin DNA Binding RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Puromycin Cellular Response To Cycloheximide Positive Regulation Of Proteolysis Carbohydrate Homeostasis Notch Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process CHOP-C/EBP Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Glucose Homeostasis Regulation Of Proteasomal Protein Catabolic Process Response To Nutrient Response To Vitamin B2 White Fat Cell Proliferation C/EBP Complex Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Negative Regulation Of Translation Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Response To Cycloheximide 5'-3' RNA Exonuclease Activity Response To Ketone Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Response To Phenylpropanoid Carbon Catabolite Regulation Of Transcription Fat Cell Proliferation G-quadruplex RNA Binding Regulation Of Transcription By Glucose G-quadruplex DNA Binding 5'-3' Exonuclease Activity Urea Cycle STAT Family Protein Binding NSL Complex Nuclear MRNA Surveillance Urea Metabolic Process HMG Box Domain Binding Response To Lithium Ion Transcription By RNA Polymerase I Regulation Of Hematopoietic Stem Cell Proliferation Cellular Response To Lithium Ion Regulation Of Protein Catabolic Process Nitrogen Cycle Metabolic Process White Fat Cell Differentiation Interleukin-6-mediated Signaling Pathway
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