DLK2

Description		delta like non-canonical Notch ligand 2
Image		No pdb structure
GO Annotations	Cellular Component	Membrane
	Molecular Function	Notch Binding Calcium Ion Binding Identical Protein Binding
	Biological Process	Regulation Of Fat Cell Differentiation Negative Regulation Of Notch Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: ADAMTSL4 APP KRTAP4-12 PLSCR1
Entrez ID		65989
HPRD ID		16855
Ensembl ID		ENSG00000171462
Uniprot IDs		Q5T3T9 Q6UY11
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Lead Ion Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Apoptotic Process Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Programmed Cell Death Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Cell Death Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Phosphatidylserine Biosynthetic Process Mercury Ion Binding Lead Ion Binding Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Pigment Cell Development Membrane Raft Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Interstitial Matrix Endoplasmic Reticulum Lumen Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Endocytosis
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