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SLC20A2
Description
solute carrier family 20 member 2
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Apical Plasma Membrane
Brush Border Membrane
Extracellular Exosome
Molecular Function
Virus Receptor Activity
Phosphate Transmembrane Transporter Activity
Sodium:phosphate Symporter Activity
Symporter Activity
Signaling Receptor Activity
Biological Process
Monoatomic Ion Transport
Sodium Ion Transport
Phosphate Ion Transport
Positive Regulation Of Bone Mineralization
Phosphate Ion Transmembrane Transport
Sodium Ion Transmembrane Transport
Symbiont Entry Into Host Cell
Pathways
Sodium-coupled phosphate cotransporters
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1)
Drugs
Diseases
GWAS
Appendicular lean mass (
33097823
)
Brain morphology (MOSTest) (
32665545
)
Glycated hemoglobin levels (
28898252
34059833
)
Hematocrit (
32888494
)
Hemoglobin levels (
32327693
)
Mean corpuscular hemoglobin concentration (
29403010
)
Mean corpuscular volume (
27863252
29403010
)
Pulse pressure (
27841878
28135244
30578418
)
Red blood cell count (
32888494
)
Novel Interacting Genes
1 novel interacting genes:
IDO1
Interacting Genes
1 interacting genes:
CCR5
Entrez ID
6575
HPRD ID
08865
Ensembl ID
ENSG00000168575
Uniprot IDs
A0A384MR38
B2RBR4
B4DJ71
Q08357
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Leukocyte Apoptotic Process
Chemokine (C-C Motif) Ligand 5 Binding
Kynurenic Acid Biosynthetic Process
Indoleamine 2,3-dioxygenase Activity
Swimming Behavior
Response To Molecule Of Bacterial Origin
Response To Lipopolysaccharide
Quinolinate Biosynthetic Process
Positive Regulation Of Chronic Inflammatory Response
Smooth Muscle Contractile Fiber
Tryptophan 2,3-dioxygenase Activity
Quinolinate Metabolic Process
L-tryptophan Catabolic Process To Kynurenine
Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum
Inflammatory Response
Negative Regulation Of Macrophage Apoptotic Process
Kynurenine Metabolic Process
L-tryptophan Catabolic Process
Regulation Of Chronic Inflammatory Response
'de Novo' NAD+ Biosynthetic Process From L-tryptophan
Positive Regulation Of T Cell Tolerance Induction
Stereocilium Bundle
Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum
Positive Regulation Of Tolerance Induction
Regulation Of T Cell Tolerance Induction
L-tryptophan Metabolic Process
Positive Regulation Of T Cell Apoptotic Process
Chemokine Receptor Activity
Dendritic Cell Migration
Dendritic Cell Chemotaxis
Response To Cholesterol
Response To Lipid
Negative Regulation Of Programmed Cell Death
C-C Chemokine Binding
C-C Chemokine Receptor Activity
Negative Regulation Of Apoptotic Process
Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity
Sarcoplasmic Reticulum Calcium Ion Transport
Negative Regulation Of Myeloid Cell Apoptotic Process
Negative Regulation Of Interleukin-10 Production
Aromatic Amino Acid Family Catabolic Process
Negative Regulation Of T Cell Apoptotic Process
NAD+ Biosynthetic Process
Regulation Of Tolerance Induction
Positive Regulation Of Type 2 Immune Response
Benzene-containing Compound Metabolic Process
Pyridine Nucleotide Biosynthetic Process
Positive Regulation Of Lymphocyte Apoptotic Process
Positive Regulation Of Leukocyte Apoptotic Process
Regulation Of Myeloid Cell Apoptotic Process
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