SLC6A13

Description		solute carrier family 6 member 13
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Basolateral Plasma Membrane Cell Projection Extracellular Exosome Presynapse
	Molecular Function	Amino Acid:sodium Symporter Activity Creatine Transmembrane Transporter Activity Gamma-aminobutyric Acid:sodium:chloride Symporter Activity Taurine:sodium Symporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity
	Biological Process	Neurotransmitter Transport Amino Acid Transport Monocarboxylic Acid Transport Taurine Transmembrane Transport Creatine Transmembrane Transport Sodium Ion Transmembrane Transport Gamma-aminobutyric Acid Reuptake Gamma-aminobutyric Acid Import Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier
Pathways		SLC-mediated transport of neurotransmitters Reuptake of GABA
Drugs		Guvacine
Diseases
GWAS		Chronic kidney disease ( 20383146) Chronotype ( 30696823) Creatinine levels ( 31015462) Diisocyanate-induced asthma ( 25918132) Estimated glomerular filtration rate ( 31451708 30604766 31015462 31152163) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate ( 29403010) Glomerular filtration rate (creatinine) ( 26831199 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Metabolite levels ( 23378610) Refractive error ( 32231278) Serum metabolite levels ( 24625756 33031748) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolites ( 26352407)
Interacting Genes		3 interacting genes: ATXN1 TRIM55 TRIM63
Entrez ID		6540
HPRD ID		10239
Ensembl ID		ENSG00000010379
Uniprot IDs		Q9NSD5
PDB IDs
Enriched GO Terms of Interacting Partners?		Poly(G) Binding POZ Domain Binding Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Ubiquitin Protein Ligase Activity Microtubule Diapedesis Muscle Atrophy Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Nuclear Inclusion Body Titin Binding Contractile Muscle Fiber Poly(U) RNA Binding Positive Regulation Of Glial Cell Proliferation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Leukocyte Migration Involved In Inflammatory Response Macrophage Migration Protein Ubiquitination Innate Immune Response M Band Negative Regulation Of Glycolytic Process Negative Regulation Of ATP Metabolic Process Protein Modification By Small Protein Conjugation Insulin-like Growth Factor Receptor Signaling Pathway Defense Response To Other Organism Defense Response To Symbiont Post-translational Protein Modification Response To Electrical Stimulus Negative Regulation Of Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Glial Cell Proliferation Lung Alveolus Development
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