GSTT2B

Description		glutathione S-transferase theta 2B
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Glutathione Transferase Activity Protein Binding Transferase Activity
	Biological Process	Glutathione Metabolic Process
Pathways		Glutathione conjugation
Drugs		Glutathione disulfide Deoxycholic acid
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		1 interacting genes: CFTR
Entrez ID		653689
HPRD ID		19212
Ensembl ID		ENSG00000133433
Uniprot IDs		P0CG30 Q6ICJ4
PDB IDs		1LJR 2LJR 3LJR 4MPG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Enamel Mineralization Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Amelogenesis ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Cellular Response To Forskolin Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Bicarbonate Transport Water Transport Multicellular Organismal-level Water Homeostasis Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Ion Transmembrane Transporter Activity Cholesterol Biosynthetic Process 14-3-3 Protein Binding Fluid Transport Transepithelial Transport Vesicle Docking Involved In Exocytosis Positive Regulation Of Transporter Activity ABC-type Transporter Activity Sterol Biosynthetic Process Chloride Channel Complex Positive Regulation Of Biomineral Tissue Development Cellular Response To CAMP Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle Docking Cholesterol Transport Clathrin-coated Endocytic Vesicle Membrane Odontogenesis Of Dentin-containing Tooth Chloride Channel Activity Multicellular Organismal-level Chemical Homeostasis Regulation Of Cellular PH Regulation Of Transmembrane Transporter Activity Membrane Docking Positive Regulation Of Exocytosis
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