SLC6A7

Description		solute carrier family 6 member 7
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synapse Synaptic Membrane
	Molecular Function	Proline:sodium Symporter Activity L-proline Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity
	Biological Process	Neurotransmitter Transport Amino Acid Transport Proline Transport Protein Catabolic Process Proline Transmembrane Transport Sodium Ion Transmembrane Transport Glycine Import Across Plasma Membrane
Pathways		SLC-mediated transport of neurotransmitters Creatine metabolism
Drugs		Proline
Diseases
GWAS		Inflammatory bowel disease ( 28067908) Mitochondrial heteroplasmy measurement ( 33731350) Recurrent major depressive disorder x sex interaction ( 34099189) Ulcerative colitis ( 28067908)
Interacting Genes		1 interacting genes: SNCA
Entrez ID		6534
HPRD ID		09371
Ensembl ID		ENSG00000011083
Uniprot IDs		Q99884
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Regulation Of SNARE Complex Assembly Negative Regulation Of Microtubule Polymerization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport Positive Regulation Of Receptor Recycling Synaptic Transmission, Dopaminergic Response To Epinephrine Positive Regulation Of Neurotransmitter Secretion Regulation Of Hydrogen Peroxide Metabolic Process Platelet Alpha Granule Membrane Dynein Complex Binding Synaptic Vesicle Priming Dopamine Transport Inclusion Body Neurotransmitter Reuptake Catecholamine Biosynthetic Process Response To Magnesium Ion Behavioral Response To Cocaine Phospholipase Binding
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