ANXA8

Description		annexin A8
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Vesicle Membrane Extracellular Matrix Late Endosome Membrane Sarcolemma
	Molecular Function	Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phospholipase A2 Inhibitor Activity Phosphatidylinositol-3,4-bisphosphate Binding Metal Ion Binding Actin Filament Binding
	Biological Process	Endosome Organization Blood Coagulation Hemostasis Endosomal Transport
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)
Interacting Genes		2 interacting genes: APP UCHL5
Entrez ID		653145
HPRD ID		18906
Ensembl ID		ENSG00000265190
Uniprot IDs		A0A087WTN9 B4DTB3 P13928 Q8N8J2
PDB IDs		1W3W 1W45
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Protein Catabolic Process Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Cellular Response To Stress Peptidase Activator Activity Cellular Response To Manganese Ion Forebrain Morphogenesis Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Chromatin Remodeling Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion
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