SLC6A2

Gene Name		solute carrier family 6 (neurotransmitter transporter), member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Neuron Projection Membrane Raft
	Molecular Function	Norepinephrine:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Alpha-tubulin Binding Beta-tubulin Binding
	Biological Process	Transport Neurotransmitter Transport Synaptic Transmission Monoamine Transport Norepinephrine Transport Response To Drug Response To Pain Transmembrane Transport
Pathways		Na+/Cl- dependent neurotransmitter transporters Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds SLC-mediated transmembrane transport
Drugs		Phentermine Tramadol Guanadrel Sulfate Reboxetine Venlafaxine Atomoxetine Amitriptyline Protriptyline Methylphenidate Imipramine Duloxetine Nortriptyline Amoxapine Mazindol Ergotamine Paroxetine Trimipramine Phenmetrazine Pseudoephedrine Cocaine Maprotiline Diethylpropion Sibutramine Chlorpheniramine Doxepin Nefazodone Desipramine Bupropion Guanethidine Orphenadrine Escitalopram Clomipramine Ephedra Ephedrine Ginkgo biloba MMDA 3,4-Methylenedioxymethamphetamine Dextroamphetamine Methamphetamine Phendimetrazine Nomifensine Amineptine Debrisoquin Milnacipran Mianserin Tapentadol Desvenlafaxine Dexmethylphenidate Levonordefrin Levomilnacipran
Diseases
GWAS
Protein-protein Interactions		2 interactors: PPP2R1A STX1A
Entrez ID		6530
HPRD ID		01232
Ensembl ID		ENSG00000103546
Uniprot IDs		B4DX48 P23975
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-serine Dephosphorylation Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Regulation Of Synaptic Vesicle Priming Synaptic Vesicle Docking Mitotic Nuclear Envelope Reassembly Synaptic Vesicle Fusion To Presynaptic Membrane Nuclear Envelope Reassembly Response To Gravity Positive Regulation Of Neurotransmitter Secretion Membrane Organization Negative Regulation Of JAK-STAT Cascade Glutamate Secretion Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Inactivation Of MAPK Activity Positive Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Synaptic Vesicle Transport Positive Regulation Of Membrane Potential Calcium Ion-dependent Exocytosis Negative Regulation Of Peptidyl-tyrosine Phosphorylation Vesicle Fusion Synaptic Vesicle Exocytosis Acid Secretion Positive Regulation Of Exocytosis Vesicle Docking Involved In Exocytosis Nuclear Envelope Organization Regulation Of Neurotransmitter Secretion Regulation Of Excitatory Postsynaptic Membrane Potential Organelle Fusion Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Component Organization Vesicle Docking Dicarboxylic Acid Transport Negative Regulation Of MAP Kinase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of JAK-STAT Cascade Membrane Docking Ceramide Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Neurotransmitter Secretion Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission Membrane Depolarization G2/M Transition Of Mitotic Cell Cycle Nucleus Organization Regulation Of DNA Replication Membrane Fusion Negative Regulation Of Protein Serine/threonine Kinase Activity
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