WNK2

Gene Name		WNK lysine deficient protein kinase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Protein Phosphorylation Negative Regulation Of Cell Proliferation Intracellular Signal Transduction Protein Autophosphorylation Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: ATXN1 DGCR14 WNK1 YWHAZ
Entrez ID		65268
HPRD ID		06951
Ensembl ID		ENSG00000165238
Uniprot IDs		F8W9F9 Q9Y3S1
PDB IDs
Enriched GO Terms of Interacting Partners?		Golgi Reassembly Negative Regulation Of Pancreatic Juice Secretion Histamine Secretion By Mast Cell Establishment Of Golgi Localization Golgi Inheritance Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Histamine Secretion Negative Regulation Of Phosphorylation Histamine Transport Positive Regulation Of Systemic Arterial Blood Pressure Golgi Localization Mast Cell Degranulation RNA Processing Production Of Molecular Mediator Involved In Inflammatory Response Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Mast Cell Mediated Immunity Lysosome Localization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mast Cell Activation Cytoplasmic Transport Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Leukocyte Degranulation Positive Regulation Of Blood Pressure Regulated Secretory Pathway Peptidyl-threonine Phosphorylation Cell-cell Signaling
Tagcloud ?		allow arf cdkn2 chromosomal comprehensive correlates downregulation enable epigenetic epigenomic grades hist1h1c hox hypermethylation hypomethylation inactivates individualized meningioma meningiomas modifications object p14 pertaining profiling thorough timp3 tp73 tumorigenesis upregulation