WNK3

Description		WNK lysine deficient protein kinase 3
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GO Annotations	Cellular Component	Cytoplasm Adherens Junction Bicellular Tight Junction
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Transmembrane Transporter Binding Protein Serine Kinase Activity Molecular Condensate Scaffold Activity Transporter Activator Activity
	Biological Process	Protein Phosphorylation Cell Volume Homeostasis DNA Damage Response Osmosensory Signaling Pathway Positive Regulation Of Sodium Ion Transport Positive Regulation Of Peptidyl-threonine Phosphorylation Intracellular Signal Transduction Maintenance Of Blood-brain Barrier Negative Regulation Of Apoptotic Process Monoatomic Ion Homeostasis Positive Regulation Of Calcium Ion Transport Renal Sodium Ion Absorption Cellular Hyperosmotic Response Protein Localization To Plasma Membrane Negative Regulation Of Pancreatic Juice Secretion Regulation Of Calcium Ion Import Membraneless Organelle Assembly Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Monoatomic Cation Transmembrane Transport Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Stimuli-sensing channels
Drugs
Diseases
GWAS		Height ( 28552196)
Interacting Genes		4 interacting genes: KLHL3 LBX1 REL TSC22D2
Entrez ID		65267
HPRD ID		02289
Ensembl ID		ENSG00000196632
Uniprot IDs		Q9BYP7
PDB IDs		5NKP 5O1V 5O21 5O23 5O26 5O2B 5O2C 8EDH 9D7Q
Enriched GO Terms of Interacting Partners?		Epithelial Tube Morphogenesis Negative Regulation Of Glutamatergic Neuron Differentiation Distal Tubule Morphogenesis NF-kappaB Complex
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