ST3GAL1

Description		ST3 beta-galactoside alpha-2,3-sialyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Golgi Apparatus Membrane Golgi Cisterna Membrane Trans-Golgi Network Membrane Extracellular Exosome Golgi Medial Cisterna Membrane Golgi Trans Cisterna Membrane
	Molecular Function	Beta-galactoside (CMP) Alpha-2,3-sialyltransferase Activity Sialyltransferase Activity Transferase Activity Glycosyltransferase Activity Beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide Alpha-2,3- Sialyltransferase
	Biological Process	Memory B Cell Differentiation N-acetylneuraminate Metabolic Process Protein Glycosylation Protein N-linked Glycosylation Lipid Metabolic Process Ganglioside Biosynthetic Process Via Lactosylceramide Protein O-linked Glycosylation Via N-acetyl-galactosamine Keratan Sulfate Proteoglycan Biosynthetic Process Viral Protein Processing Protein Modification Process Sialylation Negative Regulation Of Activated CD8-positive, Alpha-beta T Cell Apoptotic Process Protein Sialylation
Pathways		Keratan sulfate biosynthesis Sialic acid metabolism Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 30072576) Frontal fibrosing alopecia ( 30850646) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Heel bone mineral density x serum urate levels interaction ( 34046847) Intraocular pressure ( 24002674) Personality dimensions ( 23903073) Problematic alcohol use in trauma-exposed individuals ( 29082582) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Schizophrenia (negative symptoms) ( 23382809) Squamous cell carcinoma ( 26908436)
Novel Interacting Genes		1 novel interacting genes: DNAAF11
Interacting Genes		1 interacting genes: GSTA1
Entrez ID		6482
HPRD ID		06219
Ensembl ID		ENSG00000008513
Uniprot IDs		Q11201
PDB IDs
Enriched GO Terms of Interacting Partners?		Glutathione Derivative Biosynthetic Process Steroid Delta-isomerase Activity Apical Cytoplasm Protein Localization To Motile Cilium Glutathione Peroxidase Activity Linoleic Acid Metabolic Process Dynein Axonemal Particle Outer Dynein Arm Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Inner Dynein Arm Assembly Cerebrospinal Fluid Circulation Reproductive System Development Glutathione Transferase Activity Peroxidase Activity Fatty Acid Binding Prostanoid Metabolic Process Prostaglandin Metabolic Process Axonemal Dynein Complex Assembly Motile Cilium Assembly Epithelial Cilium Movement Involved In Extracellular Fluid Movement Extracellular Transport Glutathione Metabolic Process Protein Localization To Cilium Cellular Oxidant Detoxification Sulfur Compound Biosynthetic Process Xenobiotic Metabolic Process Cellular Detoxification Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Icosanoid Metabolic Process Male Gonad Development Sperm Motility Flagellated Sperm Motility Cilium-dependent Cell Motility Cilium Movement Involved In Cell Motility Olefinic Compound Metabolic Process Gonad Development Isomerase Activity Modified Amino Acid Metabolic Process Cilium Movement
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