EFCAB6

Description		EF-hand calcium binding domain 6
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Cilium Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) White coat effect (clinic systolic blood pressure minus ambulatory systolic blood pressure) ( 31044621)
Interacting Genes		3 interacting genes: AR GOLGA2 PARK7
Entrez ID		64800
HPRD ID		13391
Ensembl ID		ENSG00000186976
Uniprot IDs		Q5THR3
PDB IDs		1WLZ 5D67
Enriched GO Terms of Interacting Partners?		Androgen Receptor Signaling Pathway Single Fertilization Prostate Induction Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Male Somatic Sex Determination Glyoxal Catabolic Process L-dopa Decarboxylase Activator Activity Guanine Deglycation Protein Deglycase Activity Glyoxalase (glycolic Acid-forming) Activity Glycolate Biosynthetic Process Guanine Deglycation, Methylglyoxal Removal Guanine Deglycation, Glyoxal Removal Detoxification Of Mercury Ion Negative Regulation Of Death-inducing Signaling Complex Assembly Cellular Response To Glyoxal Glyoxal Metabolic Process Positive Regulation Of L-dopa Biosynthetic Process Tyrosine 3-monooxygenase Activator Activity Fertilization Hormone-mediated Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Lateral Sprouting Involved In Mammary Gland Duct Morphogenesis Negative Regulation Of Protein K48-linked Deubiquitination Detection Of Oxidative Stress Negative Regulation Of Nitrosative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Dopamine Biosynthetic Process Reproductive Process Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Intracellular Receptor Signaling Pathway Positive Regulation Of Integrin Biosynthetic Process Negative Regulation Of TRAIL-activated Apoptotic Signaling Pathway Superoxide Dismutase Copper Chaperone Activity Positive Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Glycolate Metabolic Process Detoxification Of Hydrogen Peroxide Regulation Of Protein K48-linked Deubiquitination Negative Regulation Of Hydrogen Peroxide-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of TRAIL Production Mercury Ion Binding Negative Regulation Of Apoptotic Signaling Pathway Male Genitalia Morphogenesis POU Domain Binding Positive Regulation Of Protein Glycosylation Cellular Detoxification Of Methylglyoxal
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