DNAI2

Description		dynein axonemal intermediate chain 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Axonemal Dynein Complex Microtubule Cilium Axoneme External Side Of Plasma Membrane Dynein Complex Sperm Flagellum Outer Dynein Arm Cell Projection Glial Cell Projection 9+2 Motile Cilium Dynein Axonemal Particle
	Molecular Function	Microtubule Motor Activity Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	Cilium Movement Determination Of Left/right Symmetry Cell Projection Organization Outer Dynein Arm Assembly Cilium Assembly
Pathways
Drugs
Diseases		Primary ciliary dyskinesia, including: Primary ciliary dyskinesia; Kartagener syndrome
GWAS		Information processing speed ( 21130836) Metabolite risk score for predicting weight gain ( 31560688)
Novel Interacting Genes		1 novel interacting genes: MFSD11
Interacting Genes		1 interacting genes: SQSTM1
Entrez ID		64446
HPRD ID		12019
Ensembl ID		ENSG00000171595
Uniprot IDs		Q9GZS0
PDB IDs		8J07
Enriched GO Terms of Interacting Partners?		Aggrephagy Lewy Body Regulation Of Protein Complex Stability Response To Mitochondrial Depolarisation Fat Cell Proliferation Negative Regulation Of Ferroptosis Protein Targeting To Vacuole Involved In Autophagy Autolysosome Brown Fat Cell Proliferation Amphisome Molecular Sequestering Activity Protein Localization To Perinuclear Region Of Cytoplasm Ubiquitin-modified Protein Reader Activity Regulation Of Ferroptosis Intracellular Membraneless Organelle Pexophagy Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Inclusion Body Positive Regulation Of Long-term Synaptic Potentiation K63-linked Polyubiquitin Modification-dependent Protein Binding Phagophore Assembly Site Ionotropic Glutamate Receptor Binding Response To Food Regulation Of Toll-like Receptor 4 Signaling Pathway Aggresome Temperature Homeostasis Regulation Of Long-term Synaptic Potentiation Cell Surface Toll-like Receptor Signaling Pathway SH2 Domain Binding Protein Kinase C Binding Sperm Midpiece Regulation Of Ras Protein Signal Transduction Toll-like Receptor 4 Signaling Pathway Molecular Condensate Scaffold Activity Protein Sequestering Activity Protein Targeting To Vacuole Cell Surface Pattern Recognition Receptor Signaling Pathway Mitophagy Sarcomere Establishment Of Protein Localization To Vacuole Response To Ischemia Receptor Tyrosine Kinase Binding Positive Regulation Of Protein Localization To Plasma Membrane Autophagy Of Mitochondrion Protein K63-linked Ubiquitination Negative Regulation Of Protein Ubiquitination Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Energy Homeostasis
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