SDHAF1

Description		succinate dehydrogenase complex assembly factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding
	Biological Process	Mitochondrial Respiratory Chain Complex II Assembly
Pathways		Maturation of TCA enzymes and regulation of TCA cycle
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Alanine aminotransferase levels ( 33339817)
Interacting Genes		3 interacting genes: CCDC136 CIDEB KRT27
Entrez ID		644096
HPRD ID		18884
Ensembl ID		ENSG00000205138
Uniprot IDs		A6NFY7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasmic Vesicle Execution Phase Of Apoptosis Organelle Organization COPI-coated Vesicle Regulation Of Triglyceride Metabolic Process Phosphatidic Acid Binding COPII Vesicle Coat Lipid Transfer Activity Lipid Droplet Fusion Lipid Droplet Organization Protein-lipid Complex Assembly Lipid Storage COPII-coated Vesicle Cargo Loading Plasma Lipoprotein Particle Assembly Intermembrane Lipid Transfer Vesicle Cargo Loading Very-low-density Lipoprotein Particle Assembly Acrosomal Membrane Acrosome Assembly Hair Follicle Morphogenesis Structural Constituent Of Skin Epidermis
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