NXN

Description		nucleoredoxin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Thioredoxin-disulfide Reductase (NADPH) Activity Oxidoreductase Activity Protein-disulfide Reductase [NAD(P)H] Activity
	Biological Process	In Utero Embryonic Development Wnt Signaling Pathway Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Ubiquitination Circulatory System Development Cellular Oxidant Detoxification
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Colorectal cancer ( 24836286 27145994) Colorectal cancer or advanced adenoma ( 30510241) Economic and political preferences ( 22566634) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Facial attractiveness (female raters) ( 30946739) Heel bone mineral density ( 30598549) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Prostate cancer ( 23535732) Taxane-induced peripheral neuropathy in breast cancer ( 29278617) Type 2 diabetes ( 23300278) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		2 interacting genes: OGT PPP2CA
Entrez ID		64359
HPRD ID		14858
Ensembl ID		ENSG00000167693
Uniprot IDs		Q6DKJ4
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Regulation Of Generation Of Precursor Metabolites And Energy RNA Polymerase II CTD Heptapeptide Repeat S7 Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S2 Phosphatase Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Regulation Of Small Molecule Metabolic Process Protein O-acetylglucosaminyltransferase Activity Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Regulation Of Protein-containing Complex Assembly Negative Regulation Of Catabolic Process Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Carbon Catabolite Regulation Of Transcription Protein Serine/threonine Phosphatase Complex Peptidyl-threonine Dephosphorylation Regulation Of Transcription By Glucose Regulation Of Phosphorus Metabolic Process NSL Complex Vascular Endothelial Cell Response To Fluid Shear Stress INTAC Complex GABA Receptor Binding FAR/SIN/STRIPAK Complex Protein Phosphatase Type 2A Complex Negative Regulation Of Glycolytic Process Response To Lead Ion Acetylglucosaminyltransferase Activity Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane RNA Polymerase II Transcription Initiation Surveillance Sin3-type Complex Negative Regulation Of Hippo Signaling Synapse Negative Regulation Of ATP Metabolic Process Histone Acetyltransferase Complex Negative Regulation Of Stem Cell Population Maintenance Negative Regulation Of Developmental Process Regulation Of Protein Localization To Synapse Regulation Of Receptor Localization To Synapse Cellular Response To Fluid Shear Stress Positive Regulation Of NLRP3 Inflammasome Complex Assembly Regulation Of Necroptotic Process Regulation Of Rac Protein Signal Transduction T Cell Homeostasis
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