SCX

Description		scleraxis bHLH transcription factor
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding
	Biological Process	Mesoderm Formation Tissue Homeostasis Endochondral Ossification Chondrocyte Differentiation Heart Valve Morphogenesis Heart Valve Formation DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Differentiation Collagen Fibril Organization BMP Signaling Pathway Developmental Process Positive Regulation Of Collagen Biosynthetic Process Skeletal Muscle Cell Differentiation Tendon Development Tendon Cell Differentiation Tendon Formation Deltoid Tuberosity Development Negative Regulation Of Apoptotic Process Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Development Sertoli Cell Differentiation Sertoli Cell Development Face Morphogenesis Regulation Of Cartilage Development Positive Regulation Of Cartilage Development Sclerotome Development Cellular Response To Mechanical Stimulus Cellular Response To CAMP Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To BMP Stimulus Positive Regulation Of Gastrulation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: MYF5 NCK2 TCF3 TCF4
Entrez ID		642658
HPRD ID		19332
Ensembl ID		ENSG00000260428
Uniprot IDs		Q7RTU7
PDB IDs
Enriched GO Terms of Interacting Partners?		E-box Binding Protein Dimerization Activity Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Cell Differentiation Cell Fate Commitment Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Transcription Regulator Complex Regulation Of Neuron Differentiation Beta-catenin-TCF7L2 Complex Vitamin D Response Element Binding Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Leukocyte Proliferation Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific TFIIB-class Transcription Factor Binding Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Regulator Complex Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Regulation Of Mononuclear Cell Proliferation B Cell Lineage Commitment Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Leukocyte Proliferation Positive Regulation Of Translation In Response To Stress Positive Regulation Of Skeletal Muscle Fiber Development Muscle Organ Morphogenesis Positive Regulation Of Developmental Process Immunoglobulin V(D)J Recombination Signal Complex Assembly Regulation Of Nucleobase-containing Compound Metabolic Process Protein Heterodimerization Activity Positive Regulation Of Lymphocyte Activation Regulation Of Translation In Response To Endoplasmic Reticulum Stress Regulation Of Translational Initiation In Response To Stress Regulation Of Skeletal Muscle Fiber Development Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Differentiation
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