SFRP5

Description		secreted frizzled related protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Wnt-protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Establishment Or Maintenance Of Cell Polarity Signal Transduction Visual Perception Negative Regulation Of Cell Population Proliferation Anatomical Structure Morphogenesis Wnt Signaling Pathway Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Non-canonical Wnt Signaling Pathway Digestive Tract Morphogenesis Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Canonical Wnt Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Non-canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 24954895) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		1 interacting genes: SFRP2
Entrez ID		6425
HPRD ID		09166
Ensembl ID		ENSG00000120057
Uniprot IDs		Q5T4F7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Dermatome Development Sclerotome Development Wnt Signaling Pathway Involved In Somitogenesis Negative Regulation Of Embryonic Development Negative Regulation Of Mesodermal Cell Fate Specification Regulation Of Midbrain Dopaminergic Neuron Differentiation Stem Cell Fate Specification Development Of Primary Male Sexual Characteristics Convergent Extension Involved In Axis Elongation Regulation Of Establishment Of Planar Polarity Mesodermal Cell Fate Specification Regulation Of Mesodermal Cell Differentiation Development Of Primary Sexual Characteristics Cellular Response To X-ray Regulation Of Dopaminergic Neuron Differentiation Cardiac Left Ventricle Morphogenesis Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cell Fate Commitment Regulation Of Stem Cell Division Striated Muscle Cell Apoptotic Process Convergent Extension Post-anal Tail Morphogenesis Endopeptidase Activator Activity Muscle Cell Apoptotic Process Negative Regulation Of Peptidyl-tyrosine Phosphorylation Digestive Tract Morphogenesis Positive Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Cell Fate Specification Chondrocyte Development Hematopoietic Stem Cell Proliferation Fibronectin Binding Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Response To X-ray Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Cardiac Ventricle Morphogenesis Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Branching Involved In Blood Vessel Morphogenesis Wnt-protein Binding Negative Regulation Of Striated Muscle Cell Apoptotic Process Neural Tube Development Somitogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Cell Fate Commitment Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Cardiac Muscle Cell Apoptotic Process Non-canonical Wnt Signaling Pathway Segmentation Embryonic Digit Morphogenesis Negative Regulation Of Muscle Cell Apoptotic Process
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