SNX16

Description		sorting nexin 16
Image
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Early Endosome Late Endosome Endosome Membrane Membrane Early Endosome Membrane Late Endosome Membrane
	Molecular Function	Lipid Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Receptor Recycling Protein Targeting To Lysosome Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (executive function) (slope of z-scores) ( 30954325) Blond vs. brown/black hair color ( 30531825) Brown vs. black hair color ( 30531825) Diastolic blood pressure ( 27841878) Fasting glucose change (short-term) ( 31263163) Heart failure ( 20445134) Ovarian cancer ( 23535730) QT interval (ambient particulate matter interaction) ( 28749367) Refractive astigmatism ( 30306274) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Rheumatic heart disease ( 34106200) Systolic blood pressure ( 27841878)
Interacting Genes		1 interacting genes: SNCA
Entrez ID		64089
HPRD ID		15411
Ensembl ID		ENSG00000104497
Uniprot IDs		P57768
PDB IDs		5GW0 5GW1
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Dopamine Uptake Involved In Synaptic Transmission Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Regulation Of SNARE Complex Assembly Negative Regulation Of Microtubule Polymerization Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway ATP Synthesis Coupled Electron Transport Positive Regulation Of Receptor Recycling Synaptic Transmission, Dopaminergic Response To Epinephrine Positive Regulation Of Neurotransmitter Secretion Regulation Of Hydrogen Peroxide Metabolic Process Platelet Alpha Granule Membrane Dynein Complex Binding Synaptic Vesicle Priming Dopamine Transport Inclusion Body Neurotransmitter Reuptake Catecholamine Biosynthetic Process Response To Magnesium Ion Behavioral Response To Cocaine Phospholipase Binding
Tagcloud ?