NEUROD6

Description		neuronal differentiation 6
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Dimerization Activity E-box Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Nervous System Development Sensory Organ Development Dentate Gyrus Development Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Axon Development
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Serum folate levels ( 29953918) Very long-chain saturated fatty acid levels (fatty acid 22:0) ( 25378659)
Interacting Genes		2 interacting genes: DSCR9 HMGB1
Entrez ID		63974
HPRD ID		11387
Ensembl ID		ENSG00000164600
Uniprot IDs		A0A090N7T3 Q96NK8
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Mismatch Repair Negative Regulation Of DNA-templated Transcription Initiation C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex Positive Regulation Of Hematopoietic Progenitor Cell Differentiation Calcium-dependent Protein Kinase Regulator Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway T-helper 1 Cell Activation Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Myeloid Progenitor Cell Differentiation Negative Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Supercoiled DNA Binding Positive Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Dendritic Cell Differentiation Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Apoptotic Cell Clearance Neutrophil Clearance DNA Geometric Change Regulation Of Glycogen Catabolic Process Bubble DNA Binding Regulation Of Apoptotic Cell Clearance Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Toll-like Receptor 9 Signaling Pathway DNA Topological Change Endothelial Cell Chemotaxis RAGE Receptor Binding Regulation Of T Cell Mediated Immune Response To Tumor Cell T-helper 1 Cell Differentiation DNA Binding, Bending Cellular Response To Interleukin-7 Response To Interleukin-7 Positive Regulation Of Monocyte Chemotactic Protein-1 Production Regulation Of Dendritic Cell Differentiation Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Phagocytosis Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Dendritic Cell Chemotaxis DNA Conformation Change Glycogen Catabolic Process Positive Regulation Of DNA Binding Macrophage Activation Involved In Immune Response Regulation Of Viral Entry Into Host Cell DNA Polymerase Binding
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