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SC5D

Description sterol-C5-desaturase
Image No pdb structure
GO Annotations Cellular Component
  • Endoplasmic Reticulum
  • Endoplasmic Reticulum Membrane
  • Membrane
Molecular Function
  • C-5 Sterol Desaturase Activity
  • Iron Ion Binding
  • Oxidoreductase Activity
  • Delta7-sterol 5(6)-desaturase Activity
Biological Process
  • Lipid Metabolic Process
  • Steroid Biosynthetic Process
  • Cholesterol Biosynthetic Process
  • Steroid Metabolic Process
  • Lipid Biosynthetic Process
  • Sterol Biosynthetic Process
  • Cholesterol Biosynthetic Process Via Desmosterol
  • Cholesterol Biosynthetic Process Via Lathosterol
  • Negative Regulation Of Ferroptosis
Pathways
  • Activation of gene expression by SREBF (SREBP)
  • Cholesterol biosynthesis via desmosterol
  • Cholesterol biosynthesis via lathosterol
Drugs
Diseases
GWAS
Novel Interacting Genes 7 novel interacting genes: CGREF1 FRMD5 RPS25 SCN4B SLC19A2 UBE4A VGLL1
Interacting Genes
Entrez ID 6309
HPRD ID 09078
Ensembl ID ENSG00000109929
Uniprot IDs O75845
PDB IDs
Enriched GO Terms of Interacting Partners?
  • Voltage-gated Sodium Channel Activity Involved In Cardiac Muscle Cell Action Potential
  • AV Node Cell Action Potential
  • Pyridoxine Transport
  • Thiamine Transmembrane Transporter Activity
  • Thiamine Transport
  • Folic Acid Transmembrane Transporter Activity
  • Thiamine Diphosphate Metabolic Process
  • Thiamine Diphosphate Biosynthetic Process
  • Thiamine Transmembrane Transport
  • Vitamin Transmembrane Transporter Activity
  • Thiamine-containing Compound Metabolic Process
  • Folic Acid Transport
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