RSU1

Description		Ras suppressor protein 1
Image
GO Annotations	Cellular Component	Cytosol Focal Adhesion Extracellular Exosome
	Molecular Function	Protein Binding
	Biological Process	Signal Transduction Ras Protein Signal Transduction Regulation Of Cell-substrate Adhesion Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of GTPase Activity
Pathways		Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Drugs
Diseases
GWAS		Adult body size ( 32376654) Bone mineral content ( 31790847) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Initial alcohol sensitivity ( 30276832) Major depressive disorder ( 29317602) Metabolite levels ( 23823483) Nicotine dependence symptom count ( 25555482) Obesity-related traits ( 23251661) Platelet count ( 32888494) Platelet distribution width ( 32888494) Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave. ( 28394258) Urinary albumin excretion ( 21355061) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)
Interacting Genes		5 interacting genes: APP GSK3B HGS LIMS1 RAF1
Entrez ID		6251
HPRD ID		01551
Ensembl ID		ENSG00000148484
Uniprot IDs		Q15404
PDB IDs		7D2S 7D2T 7D2U 7LT8 7LT9
Enriched GO Terms of Interacting Partners?		Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Protein Localization To Nucleus Neuron Projection Organization Positive Regulation Of Gene Expression Response To Amyloid-beta Positive Regulation Of Biosynthetic Process Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Intracellular Signal Transduction Cellular Response To Amyloid-beta Regulation Of Protein Catabolic Process Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cell-matrix Adhesion Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Glial Cell Development Positive Regulation Of Macromolecule Metabolic Process Amyloid-beta Complex Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Regulation Of Signal Transduction Amylin Binding Regulation Of Protein Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Toll Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Calcium-mediated Signaling Positive Regulation Of Signal Transduction Regulation Of Cell Communication Negative Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Cellular Component Biogenesis Regulation Of Catalytic Activity Epithelial To Mesenchymal Transition Regulation Of Microtubule Anchoring At Centrosome Insulin Receptor Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Mesenchymal Cell Differentiation Regulation Of Cell Population Proliferation Acetylcholine Receptor Activator Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling Lipoprotein Particle Positive Regulation Of Protein Import Regulation Of Generation Of Precursor Metabolites And Energy Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development
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