RPL15

Description		ribosomal protein L15
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribosome Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Ribosomal Subunit Synapse Ribonucleoprotein Complex
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding Cadherin Binding
	Biological Process	Cytoplasmic Translation Translation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs		(S)-3-phenyllactic acid Anisomycin Puromycin
Diseases
GWAS		Acne (severe) ( 24927181) Extremely high intelligence ( 29520040) Intelligence (MTAG) ( 29326435)
Interacting Genes		11 interacting genes: ARRB1 COPS6 DUX4 EIF4ENIF1 ETS2 FNDC3B GSK3A IL7R MEOX2 SPP1 YWHAQ
Entrez ID		6138
HPRD ID		16043
Ensembl ID		ENSG00000174748
Uniprot IDs		P61313
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7XNX 7XNY 8A3D 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Post-translational Protein Modification Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of UDP-glucose Catabolic Process Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Angiotensin Receptor Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cardiac Muscle Hypertrophy Ectodermal Cell Fate Commitment Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Interleukin-7 Receptor Activity Positive Regulation Of Estradiol Secretion Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Negative Regulation Of Developmental Growth Regulation Of Estradiol Secretion Negative Regulation Of Transmembrane Transport Regulation Of Glycogen (starch) Synthase Activity
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