PROK2

Description		prokineticin 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	G Protein-coupled Receptor Binding Protein Binding
	Biological Process	Angiogenesis Endothelial Cell Proliferation Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Spermatogenesis Circadian Rhythm Sensory Perception Of Pain Negative Regulation Of Apoptotic Process Positive Regulation Of Smooth Muscle Contraction Rhythmic Process
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases		Hypogonadotropic hypogonadism; Kallmann syndrome (KAL)
GWAS		Blood protein levels ( 30072576) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494) Serum metabolite levels (CMS) ( 31636271)
Interacting Genes		1 interacting genes: TMBIM1
Entrez ID		60675
HPRD ID		08446
Ensembl ID		ENSG00000163421
Uniprot IDs		Q9HC23
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Fas Signaling Pathway Positive Regulation Of Blood Vessel Remodeling Negative Regulation Of Fas Signaling Pathway Regulation Of Blood Vessel Remodeling Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Death Receptor Binding Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Tissue Remodeling Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Calcium Channel Activity Regulation Of Tissue Remodeling Specific Granule Membrane Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization To Cell Periphery Negative Regulation Of Catalytic Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Localization To Membrane Negative Regulation Of Neuron Apoptotic Process Calcium Ion Transmembrane Transport Negative Regulation Of Protein Localization Negative Regulation Of Apoptotic Signaling Pathway Calcium Ion Transport Regulation Of Neuron Apoptotic Process
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