RGS10

Description		regulator of G protein signaling 10
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Nuclear Body Synapse
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		G alpha (i) signalling events G alpha (i) signalling events
Drugs
Diseases
GWAS		Depressive symptoms (stressful life events interaction) ( 27529621) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Obstetric antiphospholipid syndrome ( 28424481)
Interacting Genes		10 interacting genes: ADRB2 APP CALM1 GNAI1 GNAI3 GNAO1 GNAZ GNRHR PLEKHF2 PRKACA
Entrez ID		6001
HPRD ID		04172
Ensembl ID		ENSG00000148908
Uniprot IDs		O43665
PDB IDs		2DLR 2I59 2IHB
Enriched GO Terms of Interacting Partners?		Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Guanyl Nucleotide Binding G Protein-coupled Serotonin Receptor Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex G Protein-coupled Receptor Binding G Protein-coupled Serotonin Receptor Signaling Pathway Regulation Of System Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Insulin Secretion Regulation Of Insulin Secretion Adenylate Cyclase Inhibitor Activity Adenylate Cyclase Regulator Activity Negative Regulation Of Peptide Secretion Regulation Of Protein Transport Regulation Of Peptide Hormone Secretion Modulation Of Chemical Synaptic Transmission Negative Regulation Of Protein Localization Regulation Of Transport Regulation Of Establishment Of Protein Localization Regulation Of Hormone Levels Negative Regulation Of Hormone Secretion Regulation Of Biological Quality Regulation Of Muscle System Process Regulation Of Blood Circulation Negative Regulation Of Protein Secretion Regulation Of Hormone Secretion Regulation Of Protein Secretion Cell Body Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Regulation Of Calcium-mediated Signaling GTPase Activity Signal Transduction Regulation Of Metal Ion Transport Positive Regulation Of CAMP/PKA Signal Transduction GTP Binding Negative Regulation Of Protein Transport Plasma Membrane Neuronal Dense Core Vesicle Negative Regulation Of Cell Communication Cellular Response To Oxygen-containing Compound Regulation Of Monoatomic Ion Transport Negative Regulation Of Signaling Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Transport Negative Regulation Of Establishment Of Protein Localization Positive Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Secretion By Cell
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