RASA2

Description		RAS p21 protein activator 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Phospholipid Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Signal Transduction Intracellular Signal Transduction Negative Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction
Pathways		Regulation of RAS by GAPs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29083406) Basophil count ( 32888494) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807 25673413 28892062 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body size at age 10 ( 32376654) Eosinophil count ( 32888494) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Male-pattern baldness ( 28196072) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Prion diseases ( 22210626) Red blood cell count ( 32888494) Red blood cell traits ( 23222517) Refractive error ( 32231278) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Waist circumference adjusted for body mass index ( 34021172) Weight ( 28552196) White blood cell count ( 27863252 32888494)
Novel Interacting Genes		1 novel interacting genes: GATAD2A
Interacting Genes		2 interacting genes: GNA12 HRAS
Entrez ID		5922
HPRD ID		03351
Ensembl ID		ENSG00000155903
Uniprot IDs		Q15283
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein Activity D5 Dopamine Receptor Binding GTPase Complex Phospholipase C Activator Activity Small GTPase-mediated Signal Transduction Rho-activating G Protein-coupled Receptor Signaling Pathway GTPase Activity GTP Binding Oncogene-induced Cell Senescence
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