ARHGAP23

Description		Rho GTPase activating protein 23
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome
	Molecular Function	GTPase Activator Activity
	Biological Process	Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHOA GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Cerebral amyloid angiopathy x sex interaction in Alzheimer’s disease ( 34020725) Granulocyte count ( 27863252) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Ovarian cancer ( 23535730) Red cell distribution width ( 32888494) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: RAC1 RHOA
Entrez ID		57636
HPRD ID
Ensembl ID		ENSG00000275832
Uniprot IDs		A0A9L9PXQ2 Q9P227
PDB IDs
Enriched GO Terms of Interacting Partners?		Telencephalon Cell Migration Cerebral Cortex Cell Migration Semaphorin-plexin Signaling Pathway Substrate Adhesion-dependent Cell Spreading Forebrain Cell Migration Wnt Signaling Pathway, Planar Cell Polarity Pathway Membrane Invagination Positive Regulation Of Stress Fiber Assembly Non-canonical Wnt Signaling Pathway Ficolin-1-rich Granule Membrane Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Focal Adhesion Assembly G Protein Activity Regulation Of Cell-substrate Junction Organization Regulation Of Stress Fiber Assembly Secretory Granule Membrane Ruffle Membrane Cell-matrix Adhesion Regulation Of Cell-matrix Adhesion Regulation Of Reactive Oxygen Species Metabolic Process Neuron Migration Positive Regulation Of Leukocyte Migration Cell-substrate Adhesion Establishment Or Maintenance Of Cell Polarity Regulation Of Microtubule Cytoskeleton Organization Cell-cell Junction Organization Positive Regulation Of Cytoskeleton Organization Lamellipodium Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Neuron Differentiation Positive Regulation Of Supramolecular Fiber Organization Cell Cortex Cell Morphogenesis Mitotic Cleavage Furrow Formation Regulation Of Endothelial Cell Migration Positive Regulation Of Protein-containing Complex Assembly Regulation Of Cell Junction Assembly Actin Filament Organization Postsynapse Aortic Valve Formation Positive Regulation Of Protein Phosphorylation Regulation Of Leukocyte Migration Regulation Of Actin Filament Organization Positive Regulation Of Phosphorylation Small GTPase-mediated Signal Transduction Regulation Of Cell-substrate Adhesion Positive Regulation Of Vascular Associated Smooth Muscle Contraction Endothelial Tube Lumen Extension Regulation Of Microtubule-based Process Regulation Of Cellular Component Size
Tagcloud ?