DPP10

Description		dipeptidyl peptidase like 10
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GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane
	Molecular Function	Serine-type Peptidase Activity Dipeptidyl-peptidase Activity Potassium Channel Regulator Activity Transmembrane Transporter Binding
	Biological Process	Proteolysis Protein Localization To Plasma Membrane Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Adverse response to drug ( 30420678) Alanine aminotransferase levels ( 33547301) Cadmium levels ( 26025379) Daytime sleep phenotypes ( 27126917) High chromosomal aberration frequency (chromatid type) in genotoxic compound exposure ( 31586183) Hip circumference ( 28552196) Hip circumference adjusted for BMI ( 28552196) Neuritic plaque ( 31497858) Obesity-related traits ( 23251661) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701) Plasma parathyroid hormone levels ( 30134803) Pulmonary function (FVC) x omega-3 PUFA (docosahexaenoic acid) interaction (2df) ( 30199657) Response to antidepressants in depression ( 27622933) Severe influenza A (H1N1) infection ( 26379185) Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770) Suicide attempts in major depressive disorder ( 26079190) Survival in colon cancer ( 25866641) Survival in microsatellite instability low/stable colorectal cancer ( 25866641) Systolic blood pressure in sickle cell anemia ( 24058526) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		1 interacting genes: KCND2
Entrez ID		57628
HPRD ID		07083
Ensembl ID		ENSG00000175497
Uniprot IDs		B2RCJ8 B4DKB5 Q0GLB7 Q0GLB9 Q8N608
PDB IDs		4WJL
Enriched GO Terms of Interacting Partners?		Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential A-type (transient Outward) Potassium Channel Activity Kv4.2-KChIP2 Channel Complex Locomotor Rhythm Circadian Behavior Neuronal Action Potential Neuronal Cell Body Membrane Membrane Repolarization Rhythmic Behavior Postsynaptic Specialization Membrane Plasma Membrane Raft Sensory Perception Of Pain Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Potassium Ion Transmembrane Transport Perikaryon Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Cellular Response To Hypoxia Action Potential Dendritic Spine Monoatomic Ion Channel Activity GABA-ergic Synapse Circadian Rhythm Regulation Of Postsynaptic Membrane Potential Potassium Ion Transport Monoatomic Ion Channel Complex Regulation Of Heart Contraction Muscle Contraction Protein Homooligomerization Locomotory Behavior Regulation Of Blood Circulation Muscle System Process Rhythmic Process Protein Complex Oligomerization Postsynaptic Membrane Response To Hypoxia Response To Decreased Oxygen Levels Chemical Synaptic Transmission Response To Oxygen Levels Trans-synaptic Signaling Synaptic Signaling Neuronal Cell Body Anchoring Junction
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