KLHL1

Gene Name		kelch-like family member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Dendrite Neuronal Cell Body
	Molecular Function	Actin Binding
	Biological Process	Adult Walking Behavior Dendrite Development Cerebellar Purkinje Cell Layer Development Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Bilirubin levels ( 22085899) Cognitive performance ( 19734545) Obesity-related traits ( 23251661) Response to amphetamines ( 22952603)
Protein-protein Interactions		2 interactors: BMPR1B TGFBR1
Entrez ID		57626
HPRD ID		05623
Ensembl ID		ENSG00000150361
Uniprot IDs		F5H1J3 Q8TBJ7 Q9NR64
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cartilage Development Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Gonad Development Development Of Primary Sexual Characteristics Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Skeletal System Morphogenesis Signal Transduction By Phosphorylation Sex Differentiation Ovarian Cumulus Expansion Negative Regulation Of Chondrocyte Proliferation Camera-type Eye Development Eye Development Pattern Specification Process Reproductive Structure Development Oogenesis Stage Reproductive System Development Antral Ovarian Follicle Growth Skeletal System Development Sensory Organ Development Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Parathyroid Gland Development Positive Regulation Of Cell Death Gamete Generation Negative Regulation Of Cell Proliferation Cell Morphogenesis Involved In Differentiation Developmental Process Involved In Reproduction Endothelial Cell Activation Pathway-restricted SMAD Protein Phosphorylation Sexual Reproduction Positive Regulation Of SMAD Protein Import Into Nucleus Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Regulation Of SMAD Protein Import Into Nucleus Enzyme Linked Receptor Protein Signaling Pathway Germ Cell Migration Pharyngeal System Development Retinal Ganglion Cell Axon Guidance Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Response To Cholesterol Organ Morphogenesis Reproduction Cartilage Condensation Cell Morphogenesis Negative Regulation Of Chondrocyte Differentiation Cardiac Epithelial To Mesenchymal Transition Neuron Differentiation Activin Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Proliferation
Tagcloud ?		5k3 alpl armitage beadchip bovinesnp50 bull capn1 catsper1 cohran dehygrogenase ethanolamine etnk1 friesian goldenhelix hibadh hydroxyisobutyrate kelch loc785875 mc4r pdzrn4 prkcb rs110596818 rs110827324 rs110876480 rs29011704 sire srd5a2 svs7 trim36