SYT13

Description		synaptotagmin 13
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GO Annotations	Cellular Component	Plasma Membrane Membrane Transport Vesicle Axon Synaptic Vesicle Membrane Dense Core Granule Exocytic Vesicle
	Molecular Function	SNARE Binding Calcium-dependent Phospholipid Binding Calcium Ion Sensor Activity
	Biological Process	Vesicle-mediated Transport Regulation Of Calcium Ion-dependent Exocytosis Calcium-dependent Activation Of Synaptic Vesicle Fusion Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 25673413) Depression in smokers ( 30219690) Diastolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Hip index ( 34021172) Intraocular pressure ( 29785010) Pulse pressure ( 30578418) Schizophrenia ( 27922604) Systolic blood pressure ( 30578418)
Novel Interacting Genes		2 novel interacting genes: MUC1 SGCE
Interacting Genes		1 interacting genes: NRXN1
Entrez ID		57586
HPRD ID		12128
Ensembl ID		ENSG00000019505
Uniprot IDs		Q7L8C5
PDB IDs		1WFM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Presynaptic Active Zone Assembly Positive Regulation Of Presynapse Assembly Positive Regulation Of CAMP-mediated Signaling Protein-containing Complex Assembly Involved In Synapse Maturation Vesicle Protein Complex Involved In Cell-cell Adhesion Guanylate Kinase-associated Protein Clustering Sarcoglycan Complex Negative Regulation Of Filopodium Assembly Cerebellar Granule Cell Differentiation Postsynaptic Density Protein 95 Clustering Neuronal Signal Transduction NMDA Selective Glutamate Receptor Signaling Pathway NMDA Glutamate Receptor Clustering Gamma-aminobutyric Acid Receptor Clustering Positive Regulation Of Neuromuscular Synaptic Transmission Trans-synaptic Protein Complex Gephyrin Clustering Involved In Postsynaptic Density Assembly AMPA Selective Glutamate Receptor Signaling Pathway Neuroligin Clustering Involved In Postsynaptic Membrane Assembly Neuroligin Family Protein Binding Type 1 Fibroblast Growth Factor Receptor Binding Postsynaptic Membrane Assembly Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Vocal Learning Postsynaptic Membrane Organization Positive Regulation Of Synapse Maturation Presynaptic Membrane Assembly Observational Learning Presynaptic Membrane Organization Negative Regulation Of Cell Adhesion Mediated By Integrin Synaptic Vesicle Clustering Negative Regulation Of Transcription By Competitive Promoter Binding Acetylcholine Receptor Binding Neurotransmitter-gated Ion Channel Clustering Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Mitotic G1 DNA Damage Checkpoint Signaling Dystrophin-associated Glycoprotein Complex Auditory Behavior Neuron Cell-cell Adhesion Glutamatergic Neuron Differentiation Mechanosensory Behavior Positive Regulation Of Synaptic Transmission, GABAergic Mitotic G1/S Transition Checkpoint Signaling Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Cell Differentiation In Hindbrain Vocalization Behavior Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Axonal Growth Cone
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