MARCH4

Gene Name		membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Golgi Stack Trans-Golgi Network Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process	Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS		Migraine ( 22683712)
Protein-protein Interactions		3 interactors: CD4 UBE2D1 UBE2H
Entrez ID		57574
HPRD ID		16299
Ensembl ID		ENSG00000144583
Uniprot IDs		Q9P2E8
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Induction By Virus Of Host Cell-cell Fusion Protein Palmitoleylation Protein Polyubiquitination Immune Response-regulating Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Modulation By Virus Of Host Process Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Interleukin-2 Biosynthetic Process Protein Modification By Small Protein Conjugation Protein Catabolic Process Positive Regulation Of Immune Response Cellular Protein Modification Process Protein K11-linked Ubiquitination Modulation By Virus Of Host Morphology Or Physiology Regulation Of Interleukin-2 Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Defense Response To Virus By Virus Positive Regulation Of Calcium-mediated Signaling Innate Immune Response Cellular Macromolecule Catabolic Process Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Mitotic Spindle Assembly Checkpoint Positive Regulation Of Interleukin-2 Production Defense Response To Gram-negative Bacterium Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation T Cell Selection Regulation Of Calcium-mediated Signaling Entry Into Host Cell Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Cellular Protein Metabolic Process Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Protein Metabolic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
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