PDP2

Description		pyruvate dehydrogenase phosphatase catalytic subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (acetyl-transferring)]-phosphatase Activity Hydrolase Activity Cation Binding Metal Ion Binding
	Biological Process	T-helper Cell Differentiation
Pathways		Regulation of pyruvate dehydrogenase (PDH) complex
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Diastolic blood pressure ( 30224653) HDL cholesterol levels ( 32203549)
Interacting Genes		1 interacting genes: PRKCD
Entrez ID		57546
HPRD ID		15112
Ensembl ID		ENSG00000172840
Uniprot IDs		Q9P2J9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Filopodium Assembly Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Positive Regulation Of Phospholipid Scramblase Activity Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Deoxyribonuclease Activity Positive Regulation Of Endodeoxyribonuclease Activity Protein Kinase C Signaling Termination Of Signal Transduction Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Endodeoxyribonuclease Activity Regulation Of Phospholipid Catabolic Process Endolysosome Cellular Response To Hydroperoxide Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Platelet Aggregation Insulin Receptor Substrate Binding Negative Regulation Of Homotypic Cell-cell Adhesion Regulation Of Ceramide Biosynthetic Process Regulation Of Sphingolipid Biosynthetic Process Protein Tyrosine Kinase Activator Activity Cellular Response To Angiotensin Regulation Of Superoxide Anion Generation Regulation Of Membrane Lipid Metabolic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Peptidyl-threonine Phosphorylation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Response To Hydroperoxide Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Platelet Activation Fc Receptor Mediated Stimulatory Signaling Pathway Response To Angiotensin Positive Regulation Of Lipid Catabolic Process Regulation Of Platelet Aggregation Positive Regulation Of Amide Metabolic Process Regulation Of Superoxide Metabolic Process Neutrophil Activation Fc-gamma Receptor Signaling Pathway Regulation Of Phospholipid Metabolic Process Positive Regulation Of Transporter Activity Positive Regulation Of Protein Import Into Nucleus Cellular Response To Fatty Acid Immunoglobulin Mediated Immune Response B Cell Proliferation Peptidyl-serine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity
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