PDP2

Gene Name		pyruvate dehyrogenase phosphatase catalytic subunit 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix
	Molecular Function	Magnesium-dependent Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (lipoamide)] Phosphatase Activity Metal Ion Binding
	Biological Process	Pyruvate Metabolic Process Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Peptidyl-threonine Dephosphorylation Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Regulation of pyruvate dehydrogenase (PDH) complex Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: PRKCD
Entrez ID		57546
HPRD ID		15112
Ensembl ID		ENSG00000172840
Uniprot IDs		Q9P2J9
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Interleukin-10 Production Negative Regulation Of Filopodium Assembly Interleukin-12 Production Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Ceramide Biosynthetic Process Positive Regulation Of Phospholipid Transport Negative Regulation Of Platelet Aggregation Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Superoxide Anion Generation Regulation Of Superoxide Anion Generation Regulation Of Platelet Aggregation Negative Regulation Of Platelet Activation Positive Regulation Of Protein Dephosphorylation Neutrophil Activation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Lipid Catabolic Process Regulation Of Platelet Activation Cellular Senescence Negative Regulation Of Insulin Receptor Signaling Pathway B Cell Proliferation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Filopodium Assembly Peptidyl-threonine Phosphorylation Positive Regulation Of Dephosphorylation Activation Of Phospholipase C Activity Negative Regulation Of Blood Coagulation Negative Regulation Of Protein Binding Positive Regulation Of Phospholipase C Activity Positive Regulation Of Transporter Activity Regulation Of Lipid Catabolic Process Negative Regulation Of Coagulation Positive Regulation Of Lipid Transport Positive Regulation Of Lipid Biosynthetic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Wound Healing Positive Regulation Of Response To DNA Damage Stimulus Termination Of Signal Transduction Cell Aging Negative Regulation Of Actin Filament Polymerization Execution Phase Of Apoptosis Positive Regulation Of Phospholipase Activity Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of MAP Kinase Activity Negative Regulation Of Protein Polymerization Regulation Of Phospholipase Activity
Tagcloud ?		abrogation avert begun braf coincided crafting enforced eradicated gatekeeper intimately irreversibly licensing melanomas metabolically mobilize ois pdh pdk1 perturbations players pyruvate reversion senescent tenacious therapeutically tricarboxylic unscheduled v600e withdrawing