INTS2

Gene Name		integrator complex subunit 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Membrane Integral Component Of Membrane Nuclear Membrane Integrator Complex
	Molecular Function	Protein Binding
	Biological Process	SnRNA Processing
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: KDM1A SUV39H1
Entrez ID		57508
HPRD ID		11137
Ensembl ID		ENSG00000108506
Uniprot IDs		Q9H0H0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Primitive Erythrocyte Differentiation Histone Modification Histone H3-K9 Dimethylation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Chromatin Modification Positive Regulation Of Megakaryocyte Differentiation Histone H3-K9 Trimethylation Chromatin Organization Peptidyl-lysine Dimethylation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Chromatin Silencing At RDNA Granulocyte Differentiation Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Positive Regulation Of Erythrocyte Differentiation Negative Regulation Of Circadian Rhythm Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Histone H3-K9 Methylation Chromosome Organization Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Transcription, DNA-templated Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Peptidyl-lysine Trimethylation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Chromatin Silencing Histone Demethylation Regulation Of Erythrocyte Differentiation Histone H3-K9 Modification Protein Demethylation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of DNA Binding Regulation Of Histone Methylation Positive Regulation Of Neural Precursor Cell Proliferation Pituitary Gland Development
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