SENP7

Description		SUMO specific peptidase 7
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GO Annotations	Cellular Component	Nucleus Cytoplasm Presynaptic Cytosol Postsynaptic Cytosol
	Molecular Function	Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity SUMO-specific Endopeptidase Activity
	Biological Process	Immune System Process Proteolysis Protein Desumoylation Innate Immune Response Antiviral Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 30820047) Asthma ( 32296059) Bitter alcoholic beverage consumption ( 31046077) Crohn's disease ( 28067908) Diastolic blood pressure ( 30578418) Inflammatory bowel disease ( 28067908) Leukocyte telomere length ( 32109421) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean corpuscular hemoglobin ( 27863252) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Plateletcrit ( 32888494) Red blood cell count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		1 interacting genes: SUMO2
Entrez ID		57337
HPRD ID		07154
Ensembl ID		ENSG00000138468
Uniprot IDs		J3QT09 Q9BQF6
PDB IDs		3EAY 7R2E
Enriched GO Terms of Interacting Partners?		Ubiquitin-like Protein Ligase Binding SUMO Transferase Activity Presynaptic Cytosol Postsynaptic Cytosol Protein Tag Activity Protein Sumoylation Hippocampal Mossy Fiber To CA3 Synapse Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process GABA-ergic Synapse Positive Regulation Of Proteasomal Protein Catabolic Process PML Body Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Presynapse Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Postsynapse
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