ADAMTSL3

Description		ADAMTS like 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix
	Molecular Function	Protein Binding
	Biological Process	Extracellular Matrix Organization
Pathways		Defective B3GALTL causes PpS O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS		A body shape index ( 34021172) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 33097823 28724990) Asthma ( 34103634 32296059) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder lithium response (categorical) or schizophrenia ( 29121268) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Childhood body mass index ( 33045005) Chronic obstructive pulmonary disease ( 33909500 30804561) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Height ( 19343178 28552196 20189936 31562340 18391950 18391952 33713608 18391951 20881960 21998595 23563607 20397748 25282103 25429064) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 34021172 25673412) Hip index ( 34021172) Lean body mass ( 28724990) Optic disc size ( 31809533) Pulse pressure ( 30224653) Schizophrenia ( 30285260 29483656 28991256 25056061) Spine bone size ( 31053729) Waist circumference ( 26785701) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28552196 26785701 34021172 28448500) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Novel Interacting Genes		7 novel interacting genes: ALPK3 BNC1 EFL1 GOLGA2P10 HDGFL3 IDH3A RAMAC
Interacting Genes		14 interacting genes: CYSRT1 GLRX3 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-6 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-2 KRTAP5-7 MDFI NOTCH2NLA
Entrez ID		57188
HPRD ID		12426
Ensembl ID		ENSG00000156218
Uniprot IDs		P82987
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament
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