THOC2

Description		THO complex subunit 2
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GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Speck
	Molecular Function	RNA Binding MRNA Binding Protein Binding
	Biological Process	Cell Morphogenesis Blastocyst Development MRNA Processing MRNA Export From Nucleus RNA Splicing Regulation Of Gene Expression Regulation Of MRNA Export From Nucleus Negative Regulation Of Neuron Projection Development Poly(A)+ MRNA Export From Nucleus Stem Cell Division Neuron Development Generation Of Neurons MRNA Transport
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Eosinophil count ( 32888494)
Interacting Genes		3 interacting genes: CEBPA PTEN USP7
Entrez ID		57187
HPRD ID		02317
Ensembl ID		ENSG00000125676
Uniprot IDs		Q8NI27
PDB IDs		7APK 7ZNK 7ZNL
Enriched GO Terms of Interacting Partners?		Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Synaptic Vesicle Clustering PML Body Regulation Of Osteoblast Differentiation Response To Vitamin B2 C/EBP Complex Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Proteolysis Developmental Maturation CHOP-C/EBP Complex Regulation Of Proteasomal Protein Catabolic Process Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Symbiont-mediated Disruption Of Host Cell PML Body White Fat Cell Proliferation Regulation Of Protein Metabolic Process Protein Stabilization Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Rhythmic Process Learning Or Memory Negative Regulation Of Cell Development Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Cognition Regulation Of Synaptic Vesicle Clustering Regulation Of Establishment Of Protein Localization To Telomere Response To Phenylpropanoid Negative Regulation Of Cell Cycle Intracellular Signal Transduction Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Retrograde Transport, Endosome To Golgi Regulation Of Protein Catabolic Process Fat Cell Proliferation Regulation Of Protein Stability Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size
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