GJC2

Description		gap junction protein gamma 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Gap Junction Connexin Complex Membrane Myelin Sheath Anchoring Junction
	Molecular Function	Gap Junction Channel Activity Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling
	Biological Process	Cell Communication Cell-cell Signaling Response To Toxic Substance Cell Communication By Electrical Coupling Transmembrane Transport
Pathways		Gap junction assembly
Drugs
Diseases		Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS
Interacting Genes		6 interacting genes: ADRB2 CHRM2 F2RL1 GPR35 LTB4R2 PTGER4
Entrez ID		57165
HPRD ID		10582
Ensembl ID		ENSG00000198835
Uniprot IDs		A0A654IBV7 Q5T442
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein-containing Complex Disassembly Regulation Of Systemic Arterial Blood Pressure Vasodilation Clathrin-coated Endocytic Vesicle Membrane Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Signal Transduction Regulation Of Smooth Muscle Contraction Positive Regulation Of Mini Excitatory Postsynaptic Potential Plasma Membrane T Cell Activation Involved In Immune Response Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Eosinophil Extravasation Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of System Process Beta2-adrenergic Receptor Activity Proteinase-activated Receptor Activity Positive Regulation Of Eosinophil Degranulation Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Negative Regulation Of Eosinophil Migration Leukotriene B4 Receptor Activity Lymphocyte Activation Involved In Immune Response Regulation Of Protein-containing Complex Disassembly Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Beta-adrenergic Receptor Activity Positive Regulation Of Glomerular Filtration Regulation Of Renin Secretion Into Blood Stream Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Integrin Activation Leukotriene Receptor Activity Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Blood Vessel Diameter Maintenance Norepinephrine Binding Regulation Of Tube Size Cell Activation Involved In Immune Response Leukocyte Activation Involved In Immune Response Positive Regulation Of Killing Of Cells Of Another Organism Prostaglandin Receptor Activity Leukotriene Signaling Pathway Regulation Of Blood Pressure Regulation Of Muscle Contraction Response To Psychosocial Stress Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Activity Mature Conventional Dendritic Cell Differentiation
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