JPH2

Gene Name		junctophilin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Z Disc Junctional Membrane Complex
	Molecular Function	Phosphatidylserine Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-5-phosphate Binding Calcium-release Channel Activity Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol-4-phosphate Binding Phosphatidic Acid Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Regulation Of Cardiac Muscle Tissue Development Calcium Ion Homeostasis Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: CAV3
Entrez ID		57158
HPRD ID		12006
Ensembl ID		ENSG00000149596
Uniprot IDs		Q86VZ3 Q9BR39
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction By Receptor Internalization Negative Regulation Of Sarcomere Organization Regulation Of Nerve Growth Factor Receptor Activity Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development T-tubule Organization Positive Regulation Of Caveolin-mediated Endocytosis Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Membrane Depolarization During Action Potential Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Negative Regulation Of Cardiac Muscle Cell Differentiation Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Caveolin-mediated Endocytosis Caveola Assembly Negative Regulation Of Protein Localization To Cell Surface Regulation Of Skeletal Muscle Contraction Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Plasma Membrane Repair Negative Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Muscle Hypertrophy Membrane Raft Assembly Negative Regulation Of Monooxygenase Activity Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Positive Regulation Of Microtubule Polymerization Negative Regulation Of Potassium Ion Transmembrane Transport Regulation Of P38MAPK Cascade Negative Regulation Of Cell Size Heart Trabecula Formation Regulation Of Sarcomere Organization Regulation Of Protein Localization To Cell Surface Ventricular Cardiac Muscle Cell Action Potential Negative Regulation Of Striated Muscle Cell Differentiation Membrane Raft Organization Myoblast Fusion Negative Regulation Of Cardiac Muscle Tissue Development Regulation Of Membrane Repolarization Negative Regulation Of Potassium Ion Transport Membrane Assembly Regulation Of Calcium Ion Import Negative Regulation Of Oxidoreductase Activity Membrane Biogenesis Muscle Cell Cellular Homeostasis Heart Trabecula Morphogenesis Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Microtubule Polymerization Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Hypertrophy
Tagcloud ?		125b acvr1b acvr2a arid3b bak1 bcl2l2 bear bim bmpr1b cadm1 cardio cardiology cmass e2f3 fgfr2 fgfr3 glut3 il6r men1 mirs onco orchestration raf1 sitr7 smoothened st7l twist1 wee1 wnt7a