EPPIN

Description		epididymal peptidase inhibitor
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Extracellular Space Cytoplasm Cell Surface Protein-containing Complex Sperm Plasma Membrane
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Negative Regulation Of Peptidase Activity Defense Response To Bacterium Negative Regulation Of Calcium Ion Import Negative Regulation Of Flagellated Sperm Motility
Pathways		Antimicrobial peptides
Drugs
Diseases
GWAS
Interacting Genes		2 interacting genes: CLU LTF
Entrez ID		57119
HPRD ID		10615
Ensembl ID		ENSG00000101448
Uniprot IDs		A0A384NYB9 B2R4Q0 O95925
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-binding Transcription Factor Activity Perinuclear Endoplasmic Reticulum Lumen Regulation Of Tumor Necrosis Factor Production Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Neuronal Signal Transduction Negative Regulation Of Tumor Necrosis Factor (ligand) Superfamily Member 11 Production Positive Regulation Of Neurofibrillary Tangle Assembly Humoral Immune Response Negative Regulation Of Single-species Biofilm Formation In Or On Host Organism Negative Regulation Of Activation Of Membrane Attack Complex Central Nervous System Myelin Maintenance Immune Complex Clearance Positive Regulation Of Bone Mineralization Involved In Bone Maturation Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Chromaffin Granule Phagocytic Vesicle Lumen Membrane Destabilizing Activity Positive Regulation Of Inclusion Body Assembly Negative Regulation Of Complement-dependent Cytotoxicity Neurofibrillary Tangle Positive Regulation Of Amyloid Fibril Formation Negative Regulation Of Osteoclast Development Regulation Of Neurofibrillary Tangle Assembly Protein Import Spherical High-density Lipoprotein Particle Negative Regulation Of Immune System Process Positive Regulation Of Chondrocyte Proliferation Microglial Cell Proliferation Regulation Of Osteoclast Development Positive Regulation Of Immune Response Negative Regulation Of Amyloid Fibril Formation Innate Immune Response Protein Targeting To Vacuole Involved In Autophagy Regulation Of Complement-dependent Cytotoxicity Protein Carrier Chaperone Negative Regulation Of Complement Activation Response To Misfolded Protein Cell Surface Negative Regulation Of ATP-dependent Activity Cytolysis By Host Of Symbiont Cells Negative Regulation Of Membrane Potential Specific Granule Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Antifungal Humoral Response Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Osteoblast Proliferation Myelin Maintenance Apical Dendrite Defense Response To Other Organism
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