REXO4

Description		REX4 homolog, 3'-5' exonuclease
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Speck
	Molecular Function	Nucleic Acid Binding Double-stranded DNA Binding Single-stranded DNA Binding RNA Binding Nuclease Activity Endonuclease Activity Exonuclease Activity Protein Binding 3'-5' Exonuclease Activity Hydrolase Activity
	Biological Process	DNA Metabolic Process DNA Repair DNA Catabolic Process Regulation Of DNA-templated Transcription RRNA Processing RNA Processing
Pathways
Drugs
Diseases
GWAS		ABO blood group (A vs O) ( 34202464) ABO blood group (AB vs non-AB) ( 34202464) ABO blood group (AB vs O) ( 34202464) ABO blood group (B vs non-B) ( 34202464) ABO blood group (B vs O) ( 34202464) ABO blood group (O vs non-O) ( 34202464) Malaria ( 31844061) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		5 interacting genes: BUB3 ESR1 ESR2 HSF2BP OGT
Entrez ID		57109
HPRD ID		04239
Ensembl ID		ENSG00000148300
Uniprot IDs		B4DJ95 B4E331 Q9GZR2
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Estrogen Receptor Activity Estrogen Response Element Binding Estrogen Receptor Signaling Pathway Nuclear Steroid Receptor Activity Steroid Binding Cellular Response To Estradiol Stimulus Lipid Binding Nuclear Receptor Activity Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Bub1-bub3 Complex Response To Estradiol Protein Localization To Chromosome Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of DNA-binding Transcription Factor Activity Protein Localization To Organelle Intracellular Signal Transduction Nucleoplasm Hormone-mediated Signaling Pathway Prostate Epithelial Cord Elongation Positive Regulation Of Nitric-oxide Synthase Activity Protein O-acetylglucosaminyltransferase Activity Regulation Of DNA-binding Transcription Factor Activity TFIIB-class Transcription Factor Binding Mammary Gland Branching Involved In Pregnancy Antral Ovarian Follicle Growth Mitotic Checkpoint Complex Cellular Response To Oxygen-containing Compound Regulation Of Branching Involved In Prostate Gland Morphogenesis Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Negative Regulation Of Transcription By RNA Polymerase II Intracellular Receptor Signaling Pathway Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis Regulation Of Nitric-oxide Synthase Activity Carbon Catabolite Regulation Of Transcription Female Meiosis I Rhythmic Process Nitric-oxide Synthase Regulator Activity Regulation Of Transcription By Glucose Transcription By RNA Polymerase II Prostate Gland Growth Vagina Development Double-strand Break Repair Involved In Meiotic Recombination NSL Complex
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