PDSS2

Description		decaprenyl diphosphate synthase subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol Polyprenyl Diphosphate Synthase Complex Heterotetrameric Polyprenyl Diphosphate Synthase Complex Ubiquinone Biosynthesis Complex Transferase Complex
	Molecular Function	Prenyltransferase Activity Protein Binding Transferase Activity Protein Heterodimerization Activity All-trans-nonaprenyl-diphosphate Synthase (geranyl-diphosphate Specific) Activity All-trans-decaprenyl-diphosphate Synthase Activity
	Biological Process	Lipid Metabolic Process Ubiquinone Biosynthetic Process Isoprenoid Biosynthetic Process Cerebellum Development Regulation Of Body Fluid Levels
Pathways		Ubiquinol biosynthesis
Drugs
Diseases		Coenzyme Q10 deficiency
GWAS		Airway responsiveness in chronic obstructive pulmonary disease ( 25514360) Childhood and early adolescence aggressive behavior ( 26087016) Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444) Forced expiratory volume in 1 second (environmental tobacco smoke interaction) ( 28738859) Metabolite levels ( 23823483) Microalbuminuria ( 26631737)
Interacting Genes		1 interacting genes: APP
Entrez ID		57107
HPRD ID		12879
Ensembl ID		ENSG00000164494
Uniprot IDs		B4DKU5 Q86YH6
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Neuron Projection Maintenance RAGE Receptor Binding
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