PDXP

Description		pyridoxal phosphatase
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Actin Cytoskeleton Membrane Lamellipodium Midbody Lamellipodium Membrane Cleavage Furrow Ruffle Membrane Cell Projection Contractile Ring Postsynapse Glutamatergic Synapse
	Molecular Function	Magnesium Ion Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Hydrolase Activity Phosphatase Activity Heat Shock Protein Binding Pyridoxal Phosphatase Activity Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Protein Dephosphorylation Regulation Of Mitotic Nuclear Division Dephosphorylation Positive Regulation Of Actin Filament Depolymerization Actin Rod Assembly Pyridoxal Phosphate Catabolic Process Regulation Of Cytokinesis Cellular Response To ATP Regulation Of Modification Of Postsynaptic Structure
Pathways
Drugs		Pyridoxal phosphate
Diseases
GWAS		Fat distribution (HIV) ( 21897333)
Interacting Genes		2 interacting genes: STK11 WEE2-AS1
Entrez ID		57026
HPRD ID		16468
Ensembl ID		ENSG00000241360
Uniprot IDs		A0A024R1I3 Q96GD0
PDB IDs		2CFR 2CFS 2CFT 2OYC 2P27 2P69 5GYN 8S8A 9EM1
Enriched GO Terms of Interacting Partners?		Positive T Cell Selection LRR Domain Binding Regulation Of Organelle Transport Along Microtubule Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Intracellular Protein-containing Complex Cellular Response To UV-B Positive Thymic T Cell Selection Golgi Localization Dendrite Extension Positive Regulation Of Vesicle Transport Along Microtubule Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Epithelial Cell Proliferation Involved In Prostate Gland Development Anoikis G1 To G0 Transition Pre-mRNA 5'-splice Site Binding MRNA 5'-splice Site Recognition Response To UV-B Thymic T Cell Selection Peptidyl-threonine Phosphorylation Serine/threonine Protein Kinase Complex U1 SnRNP T Cell Selection Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splice Site Recognition Activation Of Protein Kinase Activity Protein Kinase Activator Activity
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