AKR1B10

Gene Name		aldo-keto reductase family 1, member B10 (aldose reductase)
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Gene Ontology Annotations	Cellular Component	Lysosome Cytosol Extracellular Vesicular Exosome
	Molecular Function	Retinal Dehydrogenase Activity Aldo-keto Reductase (NADP) Activity Protein Binding Geranylgeranyl Reductase Activity Indanol Dehydrogenase Activity
	Biological Process	Retinoid Metabolic Process Cellular Aldehyde Metabolic Process Digestion Phototransduction, Visible Light Steroid Metabolic Process Farnesol Catabolic Process Daunorubicin Metabolic Process Doxorubicin Metabolic Process Oxidation-reduction Process
Pathways		Visual phototransduction Diseases associated with visual transduction Retinoid metabolism and transport
Drugs
Diseases
GWAS
Protein-protein Interactions		1 interactors: TERF2IP
Entrez ID		57016
HPRD ID		05271
Ensembl ID		ENSG00000198074
Uniprot IDs		O60218
PDB IDs		1ZUA 4GA8 4GAB 4GQ0 4GQG
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Recombination At Telomere Protection From Non-homologous End Joining At Telomere Protein Localization To Chromosome, Telomeric Region Telomere Capping Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Repair Regulation Of DNA Recombination Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Response To DNA Damage Stimulus Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Chromosome Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of I-kappaB Kinase/NF-kappaB Signaling DNA Replication Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		aldo atp b8 brefeldin carried classical colon colorectal ct detect elisa golgi keto located lysosomes lysosomotropic medium member murine nh4cl reductase releases sandwich secreted secretion secretory similarity