BBX

Description		BBX high mobility group box domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Bone Development
Pathways
Drugs
Diseases
GWAS		Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Depression in multiple sclerosis ( 33296963) Experiencing mood swings ( 29500382) Feeling worry ( 29500382) Height ( 31562340) Irritable mood ( 29500382) Male-pattern baldness ( 28196072) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Multisite chronic pain ( 31194737 33830993) Neurociticism ( 29500382) Neuroticism ( 29255261) Neutrophil count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Small cell lung carcinoma ( 28604730) Smoking behavior ( 19247474) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 28552196) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) White blood cell count ( 32888494)
Interacting Genes		3 interacting genes: APP NEDD4L TRIM54
Entrez ID		56987
HPRD ID		10688
Ensembl ID		ENSG00000114439
Uniprot IDs		A8K6U2 Q8WY36
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Synapse Organization Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Regulation Of Developmental Growth Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Amylin Binding Positive Regulation Of Protein Catabolic Process Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Protein Localization Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Toll Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Regulation Of Endocytosis Negative Regulation Of Sodium Ion Import Across Plasma Membrane Positive Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Potassium Ion Export Across Plasma Membrane Axon Choice Point Recognition Regulation Of Metal Ion Transport Regulation Of Caveolin-mediated Endocytosis Ubiquitin Protein Ligase Activity Regulation Of Protein Catabolic Process Heparan Sulfate Binding Signaling Receptor Activator Activity
Tagcloud ?