CA10

Description		carbonic anhydrase 10
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Carbonate Dehydratase Activity Zinc Ion Binding Hydro-lyase Activity
	Biological Process	Brain Development
Pathways
Drugs		Zonisamide
Diseases
GWAS		Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780) Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Bacterial meningitis ( 28928442) Blood protein levels ( 30072576) Chronotype ( 30696823) Femur bone mineral density x serum urate levels interaction ( 34046847) Gastritis ( 25317112) Gastroesophageal reflux disease ( 34187846 31527586) Menarche (age at onset) ( 27182965 25231870 21102462) Mercury levels ( 26025379) Metabolite levels ( 23823483) Multisite chronic pain ( 33830993) Myocardial infarction ( 33532862) Smoking initiation ( 33082346) Smoking status (ever vs never smokers) ( 30643258) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Novel Interacting Genes		1 novel interacting genes: CDK4
Interacting Genes		2 interacting genes: FXR1 SHANK3
Entrez ID		56934
HPRD ID		05224
Ensembl ID		ENSG00000154975
Uniprot IDs		A0A384MTY8 Q9NS85
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Long-term Synaptic Potentiation Regulation Of Neuronal Synaptic Plasticity Regulation Of Synaptic Transmission, Glutamatergic Cyclin D2-CDK4 Complex Cyclin D1-CDK4 Complex Cyclin D3-CDK4 Complex Regulation Of Synaptic Plasticity Positive Regulation Of Neurogenesis Dendritic Spine Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Guanylate Kinase-associated Protein Clustering Positive Regulation Of Synapse Structural Plasticity Striatal Medium Spiny Neuron Differentiation RNA Strand Annealing Activity Positive Regulation Of Nervous System Development Nuclear Pore Localization Negative Regulation Of Cell Volume AMPA Glutamate Receptor Clustering Synaptic Receptor Adaptor Activity NMDA Glutamate Receptor Clustering Cellular Response To Ionomycin Neuron Projection Intracellular Membraneless Organelle Postsynaptic Density Assembly Regulation Of Synapse Structural Plasticity Regulation Of Neurogenesis Vocal Learning Neuron Spine Cellular Response To Ether Regulation Of Type B Pancreatic Cell Proliferation Response To Phorbol 13-acetate 12-myristate Cellular Response To Phorbol 13-acetate 12-myristate Positive Regulation Of Cell Development Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Regulation Of Nervous System Development Nuclear Pore Complex Assembly Positive Regulation Of Glutamate Receptor Signaling Pathway GABAergic Neuron Differentiation Regulation Of Glutamate Receptor Signaling Pathway Observational Learning Postsynaptic Specialization Assembly Neurotransmitter-gated Ion Channel Clustering Nuclear Pore Organization Modulation Of Chemical Synaptic Transmission Auditory Behavior Costamere Ribonucleoprotein Granule
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