NMUR2

Gene Name		neuromedin U receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Neuromedin U Receptor Activity G-protein Coupled Receptor Activity Intracellular Calcium Activated Chloride Channel Activity GTP Binding Neuromedin U Binding
	Biological Process	Reduction Of Food Intake In Response To Dietary Excess Calcium Ion Transport Chloride Transport Regulation Of Smooth Muscle Contraction Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Signaling Pathway Cell-cell Signaling Central Nervous System Development Grooming Behavior Feeding Behavior Calcium-mediated Signaling Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Inositol Phosphate-mediated Signaling Response To Pain Arachidonic Acid Secretion Chloride Transmembrane Transport
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Bipolar disorder and schizophrenia ( 22688191) Optic disc size (cup) ( 20395239)
Protein-protein Interactions		6 interactors: ADAMTSL4 KRTAP13-1 NMU NOTCH2NL TCF4 TRAF2
Entrez ID		56923
HPRD ID		12003
Ensembl ID		ENSG00000132911
Uniprot IDs		Q9GZQ4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Secretion Positive Regulation Of Hormone Secretion Positive Regulation Of Binding Regulation Of Protein Binding Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Localization Maintenance Of DNA Repeat Elements Regulation Of Binding Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Regulation Of Hormone Secretion Embryonic Genitalia Morphogenesis Negative Regulation Of Glial Cell Apoptotic Process Cell Surface Receptor Signaling Pathway Myoblast Fate Commitment Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Secretion Secretory Granule Localization Positive Regulation Of Protein Homodimerization Activity Regulation Of Apoptotic Process Hindgut Morphogenesis Protein O-linked Fucosylation Gastric Acid Secretion Cellular Response To Nitric Oxide Insulin Metabolic Process Regulation Of Cell Death Regulation Of Immunoglobulin Secretion Hindgut Development Regulation Of Protein Secretion Response To Nitric Oxide Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Triglyceride Biosynthetic Process Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Gluconeogenesis Protein Homotrimerization Positive Regulation Of T Cell Cytokine Production Regulation Of Triglyceride Biosynthetic Process Genitalia Morphogenesis Regulation Of Protein Homodimerization Activity Cellular Response To Reactive Nitrogen Species Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of T Cell Cytokine Production
Tagcloud ?		alongside arcuate crapb1 crbp1 cyp26b1 ependymal f344 fall hypothalamus injections mammals melatonin neuroendocrine nutrient photoperiod photoperiodic player players probable ra raldh1 rpe65 seasonal stra6 th ttr ventricle vitamin