MCCC1

Description		methylcrotonyl-CoA carboxylase subunit 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol Methylcrotonoyl-CoA Carboxylase Complex
	Molecular Function	Nucleotide Binding Biotin Carboxylase Activity Methylcrotonoyl-CoA Carboxylase Activity Protein Binding ATP Binding Biotin Binding Ligase Activity Metal Ion Binding
	Biological Process	L-leucine Catabolic Process Biotin Metabolic Process Branched-chain Amino Acid Catabolic Process
Pathways		Biotin transport and metabolism Defective HLCS causes multiple carboxylase deficiency Branched-chain amino acid catabolism 3-Methylcrotonyl-CoA carboxylase deficiency
Drugs		Biotin
Diseases		3-Methylcrotonylglycinuria; 3-Methylcrotonyl-CoA carboxylase deficiency
GWAS		Fasting insulin ( 34074324) Lung function (FVC) ( 30175238) Lymphocyte count ( 32888494) Parkinson's disease ( 21292315 21738487 25064009 27182965 28011712 28892059 32201043 32310270) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Serum metabolite levels ( 33031748) Subjective response to lithium treatment ( 26503763)
Interacting Genes		1 interacting genes: LINC00624
Entrez ID		56922
HPRD ID		01951
Ensembl ID		ENSG00000078070
Uniprot IDs		A0A0S2Z693 E9PHF7 Q96RQ3
PDB IDs		2EJM 8J4Z 8J78 8J7D 8J99 8JAK 8JAW 8JXL 8JXM 8JXN 8K2V 8XL6 8XL7 8XL8
Enriched GO Terms of Interacting Partners?
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