GPR137

Description		G protein-coupled receptor 137
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane
	Molecular Function
	Biological Process	Autophagy Regulation Of Autophagy Negative Regulation Of Osteoclast Differentiation Negative Regulation Of Bone Resorption Positive Regulation Of TORC1 Signaling
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Crohn's disease ( 28067908) Sarcoidosis ( 22837380) Vitiligo ( 27723757) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		1 interacting genes: DRD2
Entrez ID		56834
HPRD ID		12600
Ensembl ID		ENSG00000173264
Uniprot IDs		Q96N19
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Synaptic Transmission, Glutamatergic Response To Histamine Regulation Of Synapse Structural Plasticity Dopamine Binding Regulation Of Renal Sodium Excretion Dopamine Neurotransmitter Receptor Activity Cerebral Cortex GABAergic Interneuron Migration Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Regulation Of Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway G Protein-coupled Receptor Complex Catecholamine Uptake Dopamine Uptake Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Adenohypophysis Development Negative Regulation Of Dephosphorylation Response To Inactivity Positive Regulation Of Renal Sodium Excretion Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Negative Regulation Of Neuron Migration Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Hyaloid Vascular Plexus Regression Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Neuron-neuron Synaptic Transmission Interneuron Migration From The Subpallium To The Cortex Branching Morphogenesis Of A Nerve Negative Regulation Of Dopamine Secretion Peristalsis Positive Regulation Of Growth Hormone Secretion Positive Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Uptake Involved In Synaptic Transmission Heterotrimeric G-protein Binding Regulation Of Locomotion Involved In Locomotory Behavior Positive Regulation Of Urine Volume Behavioral Response To Ethanol Negative Regulation Of Dopamine Receptor Signaling Pathway Nervous System Process Involved In Regulation Of Systemic Arterial Blood Pressure Phospholipase C-activating Dopamine Receptor Signaling Pathway Drinking Behavior Auditory Behavior Cellular Response To Ethanol Anatomical Structure Regression Negative Regulation Of Cellular Response To Hypoxia Interneuron Migration Negative Regulation Of Circadian Rhythm Grooming Behavior Regulation Of Growth Hormone Secretion Dopaminergic Synapse
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