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SUCNR1

Description succinate receptor 1
Image
GO Annotations Cellular Component
  • Plasma Membrane
  • Membrane
  • Extracellular Exosome
Molecular Function
  • G Protein-coupled Receptor Activity
  • Protein Binding
  • Signaling Receptor Activity
Biological Process
  • Renin Secretion Into Blood Stream
  • Macrophage Activation Involved In Immune Response
  • Signal Transduction
  • G Protein-coupled Receptor Signaling Pathway
  • Glucose Homeostasis
  • Positive Regulation Of Inflammatory Response
  • Positive Regulation Of Chemotaxis
  • Response To Calcium Ion
  • Regulation Of Angiotensin Metabolic Process
  • Energy Homeostasis
Pathways
  • Class A/1 (Rhodopsin-like receptors)
  • G alpha (i) signalling events
Drugs
  • Succinic acid
Diseases
GWAS
  • Gout vs. Hyperuricemia ( 31289104)
  • Immunoglobulin A ( 20694011)
  • Male-pattern baldness ( 27182965 28196072)
Interacting Genes 1 interacting genes: TMEM14B
Entrez ID 56670
HPRD ID 16211
Ensembl ID ENSG00000198829
Uniprot IDs Q9BXA5
PDB IDs 8JPN 8JPP 8WOG 8WP1 8YKV 8YKW 8YKX
Enriched GO Terms of Interacting Partners?
  • Porphyrin-containing Compound Metabolic Process
  • Pigment Metabolic Process
  • Tetrapyrrole Metabolic Process
  • Tetrapyrrole Biosynthetic Process
  • Porphyrin-containing Compound Biosynthetic Process
  • Heme Biosynthetic Process
  • Heme Metabolic Process
  • Cerebral Cortex Development
  • Neural Precursor Cell Proliferation
  • Regulation Of Cell Cycle G1/S Phase Transition
  • Regulation Of G1/S Transition Of Mitotic Cell Cycle
  • Mitochondrial Membrane
  • Regulation Of Mitotic Cell Cycle Phase Transition
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